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KMID : 1044720120020010030
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Journal of Lifestyle Medicine
2012 Volume.2 No. 1 p.30 ~ p.35
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Posttranslational Modification of PPARγ Upon Pathophysiologic Change
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Kim Ji-Hye
Jeong Yang-Sik
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Abstract
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Nuclear receptor (NR) activity is regulated in a ligand-dependent fashion and/or by post-translational modifications (PTMs) induced by a change of cellular microenvironment. In this review, we’re going to go over various PTMs for NRs and, in particular, discuss PTM-associated pathophysiological functions of peroxisome proliferator-activated receptor gamma (PPARγ) in human body.
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KEYWORD
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Nuclear receptor, Peroxisome proliferator-activated receptor gamma, Post-translational modification
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